|
Cancer Curative-Medications Guidance
As has been shown, a Cancer Forensic Map
enables the discovery of the Defect Stressor biologic of a cancer
which can be given
general
representation:
|
 |
Eq. 1 |
in which the letter 'D' represents the
defective biologic
Admittedly, medications are administered as some cancer treatments
in attempts to cure the awry-metabolism. Often though, the treatment
are trial and error, and may consists of cocktail of other tried
medications based on reports filed with Cancer Registries both at
the State and federal levels being uninformed of the specificity of
the defective biologic, in those unguided medications, the drugs
chemicals may not specifically bond with the Defect Stressor, and
may even potentially also bond the any of the neighboring biologics
and as not have curative effect as desired.
However, as observed, having knowledge of the defective biologic
offers opportunity for treatment with only such drugs that can be
pre-determined --through metabolic reaction studies; as having the
potential for specifically bonding with the Defect Stressor, and
therefore more likely to disrupt the prevailing of the cancer
So then, of significant interest is the utilizing of the knowledge
of the Defect Stressor in conjunction with medication to the end of
obtaining a cure of cancer; in effect establishing from amongst
several treatment options, the medication, M, that bonds directly with the
Defect Stressor, D such as to break up the condensation reaction
bonds to D, "...UDU...";
|
 |
Eq. 2 |
or, if the two neighboring biologics, B
react with the medication, M, then should be such that also disables
the effect of the defective gene, D, by breakup of at least one bond
of condensation reaction:
|
 |
Eq. 3 |
such as empowers medical professionals informed with
and on the specificity of drugs metabolism to confidently
effectively prescribe curative medication. The bonding of the
medication, M, to each of the biologics is made relative smaller to
emphasize that the mechanism may not necessarily be obtaining from
bio-condensation. reactions
The opportunity to be guided with the knowledge of the Defect
Stressor, such as the Computing Center can proffer with
computational Cancer Forensic Maps coupled with bioactivity
Biological Thermodynamics, therefore is a key step towards evolving
medication-based cures for all types of cancers
|
|
Medicating Cancer Genome |
|
Current
Research Activity |
Cancer Target: Colorectal Cancer
Ref. Cocktail: Publication -Public Domain
Designer:
Object: Defective Gene
Identify
Status: On-going
Proprietary: No
Access: HealthCare Medicals
Guidance†
Cocktail Reference may change with
further formalism |
|
Developing Cancer Treatment Guidance involving the administering
of medication, the representative operational genome is
generated with the Genome Facility, and several the assessments
performed on the genome collective to ascertain the curativeness
of the medication, subject to the cancer co-opting of new cells
by infiltration as well as reproduction of bona fides cancer
cells.
The primarily
consideration would be the effectiveness with which the
medication limits the paths of growth of the cancer cells. In
that sense, an essential goal would be to stem or interrupt more
than half of those paths to keep the replication rate low. Yet
at the core of this consideration lies the need to inhibit the
replication of the defective genes effectively stemming the
ignition of the cancer cells. Then, of course, just as
importantly there is the need for disabling the cell maintenance
function.
Accordingly given
the need for this multi-prong attack, the medication of
assessment often is and suggested to be a drug cocktail, such
that several paths can be simultaneously interrupted for most
effectiveness.
The effectiveness
of the medication is further improved with the determination of
the size of the cancer, and whether the cancer is of tumour or
dendrite form for the purposes of determining the extent of
tunneling through the capillaries between cells to reach into
the interior of the cancer mass. This determination is critical
to the end of evaluating the efficacy of the medicating in terms
of quantity per dosage and frequency of dosage.
As such the
cytoplasm morphology of the cancers is evaluated so the Cancer
Treatment Guidance is better informed on administering the
cocktail with respect to the rate of delivery into the cell
versus reproduction and also of the frequency of medicating
versus cell growth. Of course, the administering regime is
further refined with evaluation of the delivery process -- if
the treatment finds effect mostly within a narrow concentric
band at the surface and so inducing remission by superficial
inward-directed decrement of the size, or the cancer-wide
pervasive medicating of constituent biologics of the genome
inducing phagism of the defective gene consequent on facilitated
drug conjugates delivery into the cells
Effectively, the Cancer Treatment Guidance that obtains proffers
such a specifications the efficacy of the drug-cocktail, the
administering regime, estimated time-span of care, identity of
the role of the cocktail substances and the internal recycling
factor, and dosage frequency significance. |
|